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Losing your sense of taste could be sign of depression

By HBC Protocols December 05, 2006 0 comments

Losing our sense of taste may be an early sign of depression, say scientists. Taste is linked to the brain chemicals which control our moods, a study found. When levels of these chemicals fall, which is thought to happen when a patient is suffering depression, our sense of taste is blunted.

But boosting levels of the mood-enhancing chemicals serotonin and noradrenalin improves sense of taste, according to the researchers. The team from Bristol University say their findings could explain why loss of appetite often goes hand-in-hand with depression. Their discovery could lead to the development of a taste test allowing doctors to quickly and accurately choose the right drug to treat a patient’s depression. The study looked at the relationship between serotonin and noradrenalin and sense of taste. Volunteers were asked to taste a range of foods and their ability to pick up different tastes was rated.

They were then given antidepressants which raise the levels of serotonin or noradrenalin. The results showed that raising serotonin levels enhanced their ability to recognize bitter and sweet tastes. Raising noradrenalin levels made them more sensitive to bitter and sour tastes. St. John’s Wort improves levels of serotonin, norepinephrine and Dopamine. Dr Melichar, a psychiatrist, said: “If you can get people back to being well quicker, that is something fantastic.”

The research, which is published in the Journal Of Neuroscience, could also lead to treatments for conditions such as obesity. “It could be that some part of comfort eating is because you are eating more to get the same taste because your taste has blunted,” said Dr Melichar. “So, if you could somehow improve people’s sense of taste, they might eat less.”


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