Leber’s hereditary optic neuropathy

Leber’s hereditary optic neuropathy is maternally transmitted genetic disorder determined by acute or subacute bilateral visual loss the predominantly affects young males, sometimes as young as two years of age. Leber’s disease is characterized by degeneration of retinal ganglion cells in particular those contributing to the papillomacular bundle, leading to optic atrophy. Diagnosis is difficult—and [...]